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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
14.24
Human Site:
S140
Identified Species:
24.1
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S140
Q
Y
V
K
R
R
K
S
P
V
C
G
F
V
T
Chimpanzee
Pan troglodytes
XP_509441
819
90122
R120
S
R
I
E
I
V
I
R
E
Y
H
K
W
R
T
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
Dog
Lupus familis
XP_546925
857
93734
S140
Q
Y
V
E
R
R
K
S
P
V
C
G
F
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S140
Q
Y
V
Q
R
R
K
S
P
V
C
G
F
V
T
Rat
Rattus norvegicus
Q6AXT8
471
49872
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
N141
Q
Y
V
E
Q
R
K
N
P
V
C
G
F
I
T
Frog
Xenopus laevis
NP_001084764
548
60887
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
N144
Q
Y
V
E
K
R
Q
N
P
V
C
H
F
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
V142
R
F
S
V
A
R
Q
V
Q
Q
S
N
N
D
S
Honey Bee
Apis mellifera
XP_394429
1014
115124
T162
Q
F
I
L
K
Q
N
T
L
V
C
Q
F
A
S
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
E132
E
F
R
K
K
Q
P
E
K
P
K
K
P
F
C
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
P159
Q
F
I
L
G
R
R
P
L
I
C
Q
F
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
S171
R
E
L
L
R
L
F
S
P
L
N
P
I
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
0
93.3
N.A.
93.3
0
N.A.
N.A.
73.3
0
66.6
N.A.
6.6
26.6
6.6
26.6
P-Site Similarity:
100
26.6
0
100
N.A.
100
0
N.A.
N.A.
100
0
93.3
N.A.
33.3
66.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
8
0
29
0
0
0
8
8
0
0
0
0
0
0
% E
% Phe:
0
29
0
0
0
0
8
0
0
0
0
0
50
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
29
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
0
22
0
8
0
8
0
0
8
0
0
8
8
0
% I
% Lys:
0
0
0
15
22
0
29
0
8
0
8
15
0
0
0
% K
% Leu:
0
0
8
22
0
8
0
0
15
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
15
0
0
8
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
43
8
0
8
8
8
0
% P
% Gln:
50
0
0
8
8
15
15
0
8
8
0
15
0
0
0
% Q
% Arg:
15
8
8
0
29
50
8
8
0
0
0
0
0
8
0
% R
% Ser:
8
0
8
0
0
0
0
29
0
0
8
0
0
8
29
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
43
% T
% Val:
0
0
36
8
0
8
0
8
0
43
0
0
0
29
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
36
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _